Contribuições da enfermagem na segurança do paciente da Unidade de Terapia Intensiva: uma revisão integrativa / Nursing contributions to the patient's safety in the Intensive Care Unit: an integrative review / Contribuciones de enfermería en la Unidad de Cuidados Intensivos de seguridad del paciente: una revisión integradora

Objetivo: analisar a produção científica de enfermagem sobre a segurança do paciente na unidade de terapia intensiva. Método: revisão integrativa realizada nas bases de dados CINAHL, LILACS e SCOPUS, utilizando os descritores: patient safety/segurança do paciente, intensive care unit/unidade de terapia intensiva and nursing/enfermagem. Resultados: foram incluídos 13 artigos, analisados a partir de seis categorias: << Segurança do paciente na prevenção de eventos adversos na enfermagem >>, << Segurança do paciente na administração segura de medicamentos >>, << Segurança do paciente na comunicação efetiva >>, << Segurança do paciente na padronização de procedimentos >>, << Segurança do paciente na prevenção de úlcera por pressão >> e << Segurança do paciente na prática da higienização das mãos >>. Conclusão: os estudos apontaram como contribuições a importância da padronização dos procedimentos e quanto a baixa evidência das publicações relacionadas à enfermagem.(AU)

Objective: to analyze the scientific production on nursing related to patient's safety in the intensive care unit. Method: an integrative review conducted in CINAHL LILACS and SCOPUS databases, using the keywords: patient safety/patient safety, intensive care unit/intensive care unit and nursing/nursing. Results: the study included 13 articles analyzed from six categories: << Patient's safety in the prevention of adverse events in nursing >>, << Patient's safety in the safe administration of medication >>, << Patient's Safety in effective communication >>, << patient's Safety in the standardization of procedures >>, << patient's safety in the prevention of pressure ulcers >> and << patient's safety in the practice of handwashing >>. Conclusion: the study showed how contributions the importance of standardization of procedures and the low evidence of publications related to nursing.(AU)

Objetivo: analizar la producción científica de la enfermería en la seguridad del paciente en la unidad de cuidados intensivos. Método: una revisión integradora realizada en las bases de datos CINAHL, LILACS y SCOPUS, usando las palabras clave: la seguridad del paciente/la seguridad del paciente, unidad de cuidados intensivos/unidad de cuidados intensivos y de enfermería/ enfermería. Resultados: el estudio incluyó 13 artículos analizados a partir de seis categorías: << La seguridad del paciente en la prevención de eventos adversos en ancianos >>, << La seguridad del paciente en la administración segura de medicamentos >>, << la seguridad del paciente en la comunicación efectiva >>, << seguridad del paciente en la normalización de los procedimientos >>, << la seguridad del paciente en la prevención de úlceras por presión >> y << la seguridad del paciente en la práctica de lavado de manos >>. Conclusión: el estudio mostró cómo las contribuciones de la importancia de la normalización de los procedimientos y la escasa evidencia de publicaciones relacionadas con la enfermería.(AU)

Chronic myeloid leukemia: an overview of the determinants of effectiveness and therapeutic response in the first decade of treatment with imatinib mesylate in a Brazilian hospital.

BACKGROUND: In the last decade, there has been a revolution in chronic myeloid leukemia treatment with the introduction of tyrosine kinase inhibitors with imatinib mesylate becoming the frontline therapy. OBJECTIVE: To evaluate the therapeutic efficacy of imatinib mesylate in treating chronic myeloid leukemia patients and to identify factors related to therapeutic efficacy. METHODS: This retrospective study was based on information obtained from patients' records in the Hematology Service of Hospital Universitário Walter Cantídio of the Universidade Federal do Ceará (HUWC / UFC). All patients diagnosed with chronic myeloid leukemia that took imatinib mesylate for a minimum of 12 months in the period from January 2001 to January 2011 were included. From a population of 160 patients, 100 were eligible for analysis. RESULTS: The study population consisted of 100 patients who were mostly male (51%) with ages ranging between 21 and 40 years (42%), from the countryside (59%), in the chronic phase (95%), with high-risk prognostic factors (40%); the prognosis of high risk was not associated with complete hematologic response or complete cytogenetic response, but correlated to complete molecular response or major molecular response. Reticulin condensation was associated with complete hematologic response and complete cytogenetic response. It was found that 53% of patients had greater than 90% adherence to treatment. The high adherence was correlated to attaining complete cytogenetic response in less than 12 months. Moreover,20% of patients had good response. CONCLUSION: Significant changes are indispensable in the monitoring of patients with chronic myeloid leukemia. Thus, the multidisciplinary team is important as it provides access to the full treatment and not just to medications.

Chronic myeloid leukemia: an overview of the determinants of effectiveness and therapeutic response in the first decade of treatment with imatinib mesylate in a Brazilian hospital

Background: In the last decade, there has been a revolution in chronic myeloid leukemia treatment with the introduction of tyrosine kinase inhibitors with imatinib mesylate becoming the frontline therapy. Objective: To evaluate the therapeutic efficacy of imatinib mesylate in treating chronic myeloid leukemia patients and to identify factors related to therapeutic efficacy. Methods: This retrospective study was based on information obtained from patients'records in the Hematology Service of Hospital Universitário Walter Cantídio of the Universidade Federal do Ceará (HUWC / UFC). All patients diagnosed with chronic myeloid leukemia that took imatinib mesylate for a minimum of 12 months in the period from January 2001 to January 2011 were included. From a population of 160 patients, 100 were eligible for analysis. Results: The study population consisted of 100 patients who were mostly male (51%) with ages rangingbetween 21 and 40 years (42%), from the countryside (59%), in the chronic phase (95%), with high-riskprognostic factors (40%); the prognosis of high risk was not associated with complete hematologic responseor complete cytogenetic response, but correlated to complete molecular response or major molecularresponse. Reticulin condensation was associated with complete hematologic response and completecytogenetic response. It was found that 53% of patients had greater than 90% adherence to treatment. Thehigh adherence was correlated to attaining complete cytogenetic response in less than 12 months. Moreover,20% of patients had good response. Conclusion: Significant changes are indispensable in the monitoring of patients with chronic myeloid leukemia. Thus, the multidisciplinary team is important as it provides access to the full treatment and not just to medications. .

Diagnósticos de enfermagem identificados em pacientes transplantados renais de um hospital de ensino / Nursing diagnosis identified in renal transplant patients of a teaching hospital / Diagnósticos de enfermería identificados en pacientes transplantados renales de un hospital de enseñanza

O transplante de órgãos constitui uma última esperança de sucesso na recuperação de doenças em estágio terminal. A Enfermagem participa de forma atuante desde a captação do órgão até as consultas no ambulatório após o transplante, exigindo pessoal capacitado. Esse trabalho tem por objetivos identificar os principais diagnósticos de enfermagem em pacientes transplantados renais, em uma unidade de internação de um hospital de ensino no município de Fortaleza-Ce, e propor intervenções baseadas nas reais necessidades desses pacientes. Estudo descritivo-exploratório, de natureza qualitativa. A população foi constituída por pacientes transplantados em pós-operatório mediato e com complicações pós-transplante, sendo a amostra de doze pacientes. A coleta dos dados ocorreu através da aplicação de um histórico de enfermagem e para a análise foi abordada a seqüência das etapas do PE, utilizando-se a taxonomia II da NANDA. Foram identificados dezessete diagnósticos de enfermagem, o que permitiu a elaboração de intervenções baseadas nas reais necessidades desses pacientes. Acreditamos que, as intervenções sugeridas fundamentadas com referencial teórico, serão de suma importância para a prática dos enfermeiros que trabalham nessa área, e principalmente no hospital em questão.

The organs transplant is the last hope of success in the recovery of diseases in final stage. Nursing participates in an active way from getting the organs up till consultations after the transplant, requiring capable professionals. This paper?s goal is to identify the main nursing diagnosis in patients who underwent kidney transplant in an interned patients unit of a teaching hospital in the city of Fortaleza-CE, and propose interventions based on the real needs of these patients. Exploratory-descriptive study, with qualitative nature. The population was composed of patients in immediate post-operation and with complications, being the sample composed of twelve patients. The data collection was conducted through the application of a nursing recording and for analysis one approached the sequence of stages of NP, using the taxonomy II of NANDA. One identified seventeen nursing diagnoses, which allowed the elaboration of interventions based on the real needs of these patients. We believe that the interventions suggested based on theoretical reference, will be very important for the practice of nurses who work in this area, mainly in the hospital mentioned.

El transplante de órganos es la última esperanza de éxito en la recuperación de enfermedades terminales. La enfermería participa de manera actuante desde la captación del órgano hasta las consultas en el ambulatorio después del transplante, lo que exige personal capacitado. Este trabajo tiene por objetivo identificar los principales diagnósticos de enfermería en pacientes trasplantados renales en una unidad de internación de un hospital de enseñanza en el municipio de Fortaleza-CE y proponer intervenciones basadas en las reales necesidades de estos pacientes. Estudio descriptivo y exploratorio de naturaleza cualitativa. La población fue compuesta por pacientes transplantados en el postoperatorio inmediato y con complicaciones en el post transplante, la muestra fue de doce pacientes. La colecta de datos ocurrió a través de la aplicación de un histórico de enfermería y para el análisis fue abordada la secuencia de etapas del PE, utilizándose la taxonomia II de la NANDA. Fueron identificados diecisiete diagnósticos de enfermería, lo que permitió la elaboración de intervenciones basadas en las reales necesidades de eses pacientes. Así, creemos en la importancia para la práctica de los enfermeros que trabajan en ese área y principalmente en el hospital presentado.